Journal of Skin and Stem Cell

Review Article

28/2/2016

A Review of Acne Etiology and Treatment in Iranian Traditional Medicine

Laila Shirbeigi, Laleh Oveidzadeh, Zahra Jafari, Monireh Sadat Motahari Fard, Parvin Mansouri

Context: Iranian traditional medicine (ITM) is based on humoral theory. Temperament or Mizaj is the result of a combination of four cardinal humors. They are blood, phlegm, yellow bile (Safra) and black bile (melancholy). Like any other disease, acne is the result of humoral imbalance. Acne is a highly prevalent dermatologic problem, which has both physical and psychological effects. The aim of this study was to introduce the etiology of acne and its remedies from the perspective of ITM.

Review Article

18/3/2016

Nutritional Advice for Patients with Melasma in Iranian Traditional Medicine

Mahdis Mojtabaee, Roshanak Mokaberinejad, Samira Adhami, Parvin Mansouri, Mohammadreza Rahbar

Background: Melasma (called Kalaf in Iranian traditional medicine) is a common acquired hypermelanosis that affects sun-exposed areas of skin. Several factors including exposure to sunlight, pregnancy, and endocrine diseases increase the risk for Melasma. In traditional medicine, antecedent philosophers and physicians have tried to understand the nature and mechanisms of different systems of the human body for the diagnosis and management of Melasma; they have offered different solutions for it. This study is important since Melasma is a disease causing mental side effects in patients, due to darkness and opacity of the skin; therefore, the treatment of Melasma in terms of its psychological complications is of particular importance. In addition, texts of Iranian traditional medicine contain a wealth of nutritional advice for patients with Melasma. These texts have, until now, not yet been reviewed. The present study has considered the most important references of Iranian traditional medicine texts.

Research Article

28/3/2016

Myogenic Differentiation Potential of Human Newborn Foreskin Stem Cells Combined with Polycaprolactone-Based Nanofiber

Ozge Sezin Somuncu, Ezgi Kasikci, Salih Somuncu, Pakize Neslihan Tasli, Fikrettin Sahin

A previous study performed by the authors of the current study revealed the characterization and differentiation of newly defined stem cells known as human newborn foreskin stem cells (hnFSSCs). According to their stem cell properties, this study aimed at investigating myogenic differentiation and related tissue engineering. Human newborn foreskin stem cells were characterized by flow cytometry. The results showed that hnFSSCs carries a noble prospective for myogenic differentiation and can be used as a beneficial method for muscle related diseases, including muscular dystrophy, neuromuscular disorders, muscle damages, muscle weakness, lesion formations, and other problems associated with tissue obtainability and multi-potency; these cells may be accepted as effortlessly accessible and functional, and even superior to other stem cell origins. Furthermore, hnFFSCs were also seeded onto 3D micro-wells and Polycaprolactone (PCL) scaffolds in order to examine tissue development. Human newborn foreskin stem cells on PCL scaffolds showed good cell-cell integration, so that they may be thought as a stem cell basis for tissue engineering.

Case Report

29/12/2015

Successful Treatment of Resistant Discoid Lupus Erythematous (DLE) With Low-Level Laser Therapy (LLLT): A Case Report

Nooshafarin Kazemikhoo, Parvin Mansouri

Case Presentation: The case was a 33-year-old female with two years history of DLE, who referred to the laser clinic of Milad hospital with acute flare of skin lesions since seven months ego. She had four lesions (three with local alopecia, scaling and itching and one with atrophy). Serological studies for antinuclear antibodies and anti Ro/SS-A antibody were negative. After five sessions of treatment with infrared (830 nm; 200 mw) and red light (630 nm; 20 mw) diode laser in addition to intravenous red light laser (655 nm; 2 mw) for 20 minutes and laser acupuncture with infrared diode laser (1 J/cm²) for six acupuncture points every other day, the beneficial effects started to appear, and after nine sessions, local itching of the lesions had stopped. Through a total of 27 sessions of treatment, the lesions improved completely with highly satisfactory results; and drug-therapy held to be continued. No disease flare up was seen after the one-year follow up.

Rapid Communication

30/3/2016

Detection of Murine TRPA1 Transcripts in Keratinocytes

Kelvin Y Kwan

Journal of Skin and Stem Cell: Mar 2016, 3 (1), 5 articles.