Journal of Skin and Stem Cell

Published by: Kowsar

Successful Treatment of Epidermolysis Bullosa Pruriginosa with Oral Cyclosporine

Afsaneh Sadeghzadeh Bazargan 1 , Fahimeh Abdollahimajd 2 , Parviz Toosi 2 and Zahra Azizian 1 , *
Authors Information
1 Iran University of Medical Sciences, Tehran, IR Iran
2 Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Article information
  • Journal of Skin and Stem Cell: December 2017, 4 (3-4); e74254
  • Published Online: September 30, 2017
  • Article Type: Case Report
  • Received: July 12, 2017
  • Revised: August 20, 2017
  • Accepted: September 11, 2017
  • DOI: 10.5812/jssc.74254

To Cite: Sadeghzadeh Bazargan A, Abdollahimajd F, Toosi P, Azizian Z. Successful Treatment of Epidermolysis Bullosa Pruriginosa with Oral Cyclosporine, J Skin Stem Cell. 2017 ; 4(3-4):e74254. doi: 10.5812/jssc.74254.

Copyright © 2017, Journal of Skin and Stem Cell. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited
1. Introduction
2. Case Presentation
3. Discussion
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  • 2. McGrath JA, Schofield OM, Eady RA. Epidermolysis bullosa pruriginosa: dystrophic epidermolysis bullosa with distinctive clinicopathological features. Br J Dermatol. 1994;130(5):617-25. [PubMed: 8204470].
  • 3. Wojnarowska F, Eady RA, Burge SM. Bullous eruptions. In: Champion RH, Burton JL, Burn DA, Breathnach SM, editors. Rook/ Wilkinson/ Ebling Textbook of Dermatology. Oxford: Blackwell Science; 1998. p. 1817-97.
  • 4. Cambiaghi S, Brusasco A, Restano L, Cavalli R, Tadini G. Epidermolysis bullosa pruriginosa. Dermatology. 1997;195(1):65-8. doi: 10.1159/000245691. [PubMed: 9267744].
  • 5. Murata T, Masunaga T, Shimizu H, Takizawa Y, Ishiko A, Hatta N, et al. Glycine substitution mutations by different amino acids in the same codon of COL7A1 lead to heterogeneous clinical phenotypes of dominant dystrophic epidermolysis bullosa. Arch Dermatol Res. 2000;292(10):477-81. [PubMed: 11142768].
  • 6. Banky JP. Successful Treatment of Epidermolysis Bullosa Pruriginosa With Topical Tacrolimus. Arch Dermatol. 2004;140(7):794. doi: 10.1001/archderm.140.7.794.
  • 7. Tarutani M, Shiga T, Nakajima K, Nakano H, Sawamura D, Sano S. Dystrophic epidermolysis bullosa pruriginosa in a mother and daughter successfully treated by low dose cyclosporine. Eur J Dermatol. 2013;23(5):727-9. doi: 10.1684/ejd.2013.2126. [PubMed: 24126452].
  • 8. Takahashi T, Mizutani Y, Ito M, Nakano H, Sawamura D, Seishima M. Dystrophic epidermolysis bullosa pruriginosa successfully treated with immunosuppressants. J Dermatol. 2016;43(11):1391-2. doi: 10.1111/1346-8138.13406.
  • 9. Ozanic Bulic S, Fassihi H, Mellerio JE, McGrath JA, Atherton DJ. Thalidomide in the management of epidermolysis bullosa pruriginosa. Br J Dermatol. 2005;152(6):1332-4. doi: 10.1111/j.1365-2133.2005.06492.x. [PubMed: 15949003].

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