Journal of Skin and Stem Cell

Published by: Kowsar

Herbal Drugs with Promising Anti-Leishmanial Activity: New Hope for Leishmaniasis Treatment

Maryam Heidari-Kharaji 1 , * , Alireza Badirzadeh 2 , 3 , Fatemeh Khadir 4 , Mohsen Soori 5 and Mohammad Ali Nilforoushzadeh 1
Authors Information
1 Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IR Iran
2 Department of Medical Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
3 Department of Parasitology and Mycology, School of Medicine, Iran University of Medical Sciences, Tehran, IR Iran
4 Department of Pathobiology School of Veterinary Medicine, Shiraz University, Shiraz, IR Iran
5 Department of Surgery, school of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran
Article information
  • Journal of Skin and Stem Cell: June 2016, 3 (2); e66527
  • Published Online: June 19, 2016
  • Article Type: Review Article
  • Received: March 30, 2016
  • Revised: April 27, 2016
  • Accepted: May 22, 2016
  • DOI: 10.5812/jssc.66527

To Cite: Heidari-Kharaji M, Badirzadeh A, Khadir F, Soori M, Nilforoushzadeh M A. et al. Herbal Drugs with Promising Anti-Leishmanial Activity: New Hope for Leishmaniasis Treatment, J Skin Stem Cell. 2016 ;3(2):e66527. doi: 10.5812/jssc.66527.

Abstract
Copyright © 2016, Journal of Skin and Stem Cell. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Context
2. Evidence Acquisition
3. Results
4. Conclusions
References
  • 1. Kharaji MH, Doroud D, Taheri T, Rafati S. Drug Targeting to Macrophages With Solid Lipid Nanoparticles Harboring Paromomycin: an In Vitro Evaluation Against L. major and L. tropica. AAPS PharmSciTech. 2016;17(5):1110-9. doi: 10.1208/s12249-015-0439-1. [PubMed: 26552399].
  • 2. Badirzadeh A, Taheri T, Taslimi Y, Abdossamadi Z, Heidari-Kharaji M, Gholami E, et al. Arginase activity in pathogenic and non-pathogenic species of Leishmania parasites. PLoS Negl Trop Dis. 2017;11(7). e0005774. doi: 10.1371/journal.pntd.0005774. [PubMed: 28708893].
  • 3. Heidari-Kharaji M, Taheri T, Doroud D, Habibzadeh S, Badirzadeh A, Rafati S. Enhanced paromomycin efficacy by solid lipid nanoparticle formulation against Leishmania in mice model. Parasite Immunol. 2016;38(10):599-608. doi: 10.1111/pim.12340. [PubMed: 27213964].
  • 4. Heidari-Kharaji M, Taheri T, Doroud D, Habibzadeh S, Rafati S. Solid lipid nanoparticle loaded with paromomycin: in vivo efficacy against Leishmania tropica infection in BALB/c mice model. Appl Microbiol Biotechnol. 2016;100(16):7051-60. doi: 10.1007/s00253-016-7422-y. [PubMed: 26960322].
  • 5. Hepburn NC. Cutaneous leishmaniasis: an overview. J Postgraduate Med. 2003;49(1):50.
  • 6. Reithinger R, Dujardin JC, Louzir H, Pirmez C, Alexander B, Brooker S. Cutaneous leishmaniasis. Lancet Infect Dis. 2007;7(9):581-96. doi: 10.1016/S1473-3099(07)70209-8. [PubMed: 17714672].
  • 7. Camacho MR, Phillipson JD, Croft SL, Solis PN, Marshall SJ, Ghazanfar SA. Screening of plant extracts for antiprotozoal and cytotoxic activities. J Ethnopharmacol. 2003;89(2-3):185-91. doi: 10.1016/s0378-8741(03)00269-1.
  • 8. Sen R, Chatterjee M. Plant derived therapeutics for the treatment of Leishmaniasis. Phytomedicine. 2011;18(12):1056-69. doi: 10.1016/j.phymed.2011.03.004. [PubMed: 21596544].
  • 9. Jaffary F, Nilforoushzadeh MA, Moradi S, Derakhshan R, Ansari N. Concentrated Extracts of Cassia fistula Versus Intralesional Injection of Meglumine Antimoniate in Treatment of Acute Cutaneous Leishmaniasis. J Skin Stem Cell. 2014;1(1). doi: 10.17795/jssc16631.
  • 10. Moghaddas E, Khamesipour A, Mohebali M, Fata A. Iranian Native Plants on Treatment of Cutaneous Leishmaniosis: A Narrative Review. Iran J Parasitol. 2017;12(3):312-22. [PubMed: 28979340].
  • 11. Jameel M, Islamuddin M, Ali A, Afrin F, Ali M. Isolation, characterization and antimicrobial evaluation of a novel compound N-octacosan 7beta ol, from Fumaria parviflora Lam. BMC Complement Altern Med. 2014;14:98. doi: 10.1186/1472-6882-14-98. [PubMed: 24621260].
  • 12. Mothana RA, Al-Musayeib NM, Al-Ajmi MF, Cos P, Maes L. Evaluation of the in vitro antiplasmodial, antileishmanial, and antitrypanosomal activity of medicinal plants used in Saudi and Yemeni traditional medicine. Evid Base Complement Alternat Med. 2014;2014.
  • 13. Mahmoudvand H, Sharififar F, Sharifi I, Ezatpour B, Fasihi Harandi M, Makki MS, et al. In Vitro Inhibitory Effect of Berberis vulgaris (Berberidaceae) and Its Main Component, Berberine against Different Leishmania Species. Iran J Parasitol. 2014;9(1):28-36. [PubMed: 25642257].
  • 14. Martin-Quintal Z, Moo-Puc R, Gonzalez-Salazar F, Chan-Bacab MJ, Torres-Tapia LW, Peraza-Sanchez SR. In vitro activity of Tridax procumbens against promastigotes of Leishmania mexicana. J Ethnopharmacol. 2009;122(3):463-7. doi: 10.1016/j.jep.2009.01.037. [PubMed: 19429313].
  • 15. Chan-Bacab MJ, Balanza E, Deharo E, Munoz V, Garcia RD, Pena-Rodriguez LM. Variation of leishmanicidal activity in four populations of Urechites andrieuxii. J Ethnopharmacol. 2003;86(2-3):243-7. [PubMed: 12738094].
  • 16. Et-Touys A, Fellah H, Sebti F, Mniouil M, Aneb M, Elboury H, et al. In vitro Antileishmanial Activity of Extracts from Endemic Moroccan Medicinal Plant Salvia verbenaca (L.) Briq. ssp verbenaca Maire (S. clandestina Batt. non L). Eur J Med Plants. 2016;16(1):1-8. doi: 10.9734/ejmp/2016/27891.
  • 17. Ezatpour B, Saedi Dezaki E, Mahmoudvand H, Azadpour M, Ezzatkhah F. In vitro and in vivo antileishmanial effects of Pistacia khinjuk against Leishmania tropica and Leishmania major. Evid Base Complement Alternat Med. 2015;2015.
  • 18. Khan MJ, Baloch NU, Nabi S, Ahmed N, Bazai Z, Yasinzai M, et al. Antileishmanial, cytotoxic, antioxidant activities and phytochemical analysis of Rhazya stricta Decne leaves extracts and its fractions. Asian J Plant Sci Res. 2012;2(5):593-8.
  • 19. Nizam B, Sajid N, Kakar AM, Zargoona W, Al-Kahraman YM. In vitro antileishmanial, antitumor, cytotoxic activities and phyto-chemical analysis of Citrullus colocynthis fruit extract and its fractions. Int J Med Aromat Plants. 2013;3(1):78-84.
  • 20. Andrade MA, Azevedo CD, Motta FN, Santos ML, Silva CL, Santana JM, et al. Essential oils: in vitro activity against Leishmania amazonensis, cytotoxicity and chemical composition. BMC Complement Altern Med. 2016;16(1):444. doi: 10.1186/s12906-016-1401-9. [PubMed: 27825341].
  • 21. Abouhosseini Tabari M, Youssefi MR, Moghaddas E, Ebrahimi MA, Nabavi Mousavi N, Naseri A. Antileashmanial activity of Artemisia sieberi essential oil against Leishmania infantum in vitro. Adv Herb Med. 2016;2(2):40-6.
  • 22. Maleki F, Zarebavani M, Mohebali M, Dayer MS, Hajialiani F, Tabatabaie F. In vitro and in vivo susceptibility of Leishmania major to some medicinal plants. Asian Pac J Trop Biomed. 2017;7(1):37-42. doi: 10.1016/j.apjtb.2016.11.008.
  • 23. Mesa LE, Vasquez D, Lutgen P, Velez ID, Restrepo AM, Ortiz I, et al. In vitro and in vivo antileishmanial activity of Artemisia annua L. leaf powder and its potential usefulness in the treatment of uncomplicated cutaneous leishmaniasis in humans. Rev Soc Bras Med Trop. 2017;50(1):52-60. doi: 10.1590/0037-8682-0457-2016. [PubMed: 28327802].
  • 24. Germonprez N, Maes L, Van Puyvelde L, Van Tri M, Tuan DA, De Kimpe N. In vitro and in vivo anti-leishmanial activity of triterpenoid saponins isolated from Maesa balansae and some chemical derivatives. J Med Chem. 2005;48(1):32-7. doi: 10.1021/jm031150y. [PubMed: 15633999].
  • 25. Maes L, Vanden Berghe D, Germonprez N, Quirijnen L, Cos P, De Kimpe N, et al. In vitro and in vivo activities of a triterpenoid saponin extract (PX-6518) from the plant Maesa balansae against visceral leishmania species. Antimicrob Agents Chemother. 2004;48(1):130-6. [PubMed: 14693530].
  • 26. Nilforoushzadeh MA, Shirani-Bidabadi L, Zolfaghari-Baghbaderani A, Saberi S, Siadat AH, Mahmoudi M. Comparison of Thymus vulgaris (Thyme), Achillea millefolium (Yarrow) and propolis hydroalcoholic extracts versus systemic glucantime in the treatment of cutaneous leishmaniasis in balb/c mice. J Vector Borne Dis. 2008;45(4):301-6. [PubMed: 19248657].
  • 27. Fata A, Rakhshandeh H, Berenji F, Jalalian FA. Treatment of cutaneous leishmaniasis in murine model by alcoholic extract of Berberis vulgaris. Iran J Parasitol. 2006;1(1):39-42.
  • 28. Doroudgar A, Arbabi M, Razavi MR, Mohebali M, Sadr F. Treatment of cutaneous leishmaniasis in murine model by hydro alcoholic essence of Artemisia sieberi. J Arthropod Borne Dis. 2008;2(2):42-7.
  • 29. Marango SN, Khayeka-Wandabwa C, Makwali JA, Jumba BN, Choge JK, Adino EO, et al. Experimental therapeutic assays of Tephrosia vogelii against Leishmania major infection in murine model: in vitro and in vivo. BMC Res Notes. 2017;10(1):698. doi: 10.1186/s13104-017-3022-x. [PubMed: 29208030].
  • 30. Metwally DM, Al-Olayan EM, El-Khadragy MF, Alkathiri B. Anti-Leishmanial Activity (In Vitro and In Vivo) of Allicin and Allicin Cream Using Leishmania major (Sub-strain Zymowme LON4) and Balb/c Mice. PLoS One. 2016;11(8). e0161296. doi: 10.1371/journal.pone.0161296. [PubMed: 27537199].
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:

Author(s):

Article(s):

Create Citiation Alert
via Google Reader

Readers' Comments