Journal of Skin and Stem Cell

Published by: Kowsar

The Relationship Between Herbal Anticoagulants and Melasma

Marjan Mahjour 1 , Arash Khoushabi 2 , Mohammad Reza Noras 1 and Roshanak Salari 3 , *
Authors Information
1 Department of Persian Medicine, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
2 Health center, Mashhad University of Medical Sciences, Mashhad, Iran
3 Assistant Professor of Drug Control, Department of Clinical Persian Pharmacy, School of Persian and Complementary Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
Article information
  • Journal of Skin and Stem Cell: June 2016, 3 (2); e65578
  • Published Online: June 20, 2016
  • Article Type: Rapid Communication
  • Received: May 2, 2016
  • Revised: June 1, 2016
  • Accepted: June 15, 2016
  • DOI: 10.5812/jssc.65578

To Cite: Mahjour M, Khoushabi A, Noras M R, Salari R. The Relationship Between Herbal Anticoagulants and Melasma, J Skin Stem Cell. 2016 ; 3(2):e65578. doi: 10.5812/jssc.65578.

Copyright © 2016, Journal of Skin and Stem Cell. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Context
2. Evidence Acquisition
3. Results
4. Conclusion
  • 1. Kang HY, Ortonne JP. What should be considered in treatment of melasma. Ann Dermatol. 2010;22(4):373-8. doi: 10.5021/ad.2010.22.4.373. [PubMed: 21165205].
  • 2. Sarkar R, Arora P, Garg VK, Sonthalia S, Gokhale N. Melasma update. Indian Dermatol Online J. 2014;5(4):426-35. doi: 10.4103/2229-5178.142484. [PubMed: 25396123].
  • 3. Kim EH, Kim YC, Lee ES, Kang HY. The vascular characteristics of melasma. J Dermatol Sci. 2007;46(2):111-6. doi: 10.1016/j.jdermsci.2007.01.009. [PubMed: 17363223].
  • 4. Park KC, Kim IS. Pathogenesis of Melasma. Melasma and Vitiligo in Brown Skin. Springer; 2017. p. 21-31.
  • 5. Sonthalia S. Etiopathogenesis of melasma. Melasma: A Monograph New Delhi: Jaypee. 2015. p. 6-14.
  • 6. Shirbeigi L, Ranjbar M, Malihe T. "Vascular etiology of melasma" the idea which was first presented by avicenna and rhazes. Tradit Integr Med. 2016;1(4):166-7.
  • 7. Lee GY, Kim HJ, Whang KK. The effect of combination treatment of the recalcitrant pigmentary disorders with pigmented laser and chemical peeling. Dermatol Surg. 2002;28(12):1120-3. discussion 1123. doi: 10.1097/00042728-200212000-00005. [PubMed: 12472490].
  • 8. Rokhsar CK, Fitzpatrick RE. The treatment of melasma with fractional photothermolysis: a pilot study. Dermatol Surg. 2005;31(12):1645-50. doi: 10.2310/6350.2005.31302. [PubMed: 16336881].
  • 9. Kang HY. Melasma and aspects of pigmentary disorders in Asians. Ann Dermatol Venereol. 2012;139 Suppl 4:S144-7. doi: 10.1016/S0151-9638(12)70126-6. [PubMed: 23522629].
  • 10. Webb NJ, Bottomley MJ, Watson CJ, Brenchley PE. Vascular endothelial growth factor (VEGF) is released from platelets during blood clotting: implications for measurement of circulating VEGF levels in clinical disease. Clin Sci (Lond). 1998;94(4):395-404. doi: 10.1042/cs0940395. [PubMed: 9640345].
  • 11. Kim MB, Song. M , Mun JH, Kim SH, Jung DS. Korean red ginseng powder in the treatment of melasma. Pigment Cell Melanoma Res. 2009;22(3):367.
  • 12. Fabbrocini G, De Vita V, Marasca C, Palmisano F, Monfrecola G. Salicylic acid for the treatment of melasma: new acquisitions for monitoring the clinical improvement. Skin Res Technol. 2013;19(4):466-73. doi: 10.1111/srt.12070. [PubMed: 23527534].
  • 13. Clissold SP. Aspirin and related derivatives of salicylic acid. Drugs. 1986;32 Suppl 4:8-26. doi: 10.2165/00003495-198600324-00003. [PubMed: 3552588].
  • 14. Hafner-Blumenstiel V. [Herbal drug-drug interaction and adverse drug reactions]. Ther Umsch. 2011;68(1):54-7. doi: 10.1024/0040-5930/a000120. [PubMed: 21184395].
  • 15. Life C, Herbs G, Pharm H, Hill H, Naturals N, Naturally T. French maritime pine bark extract (Pinus pinaster). 2011. Available from:
  • 16. Mojtabaee M, Mokaberinejad R, Adhami S, Mansouri P, Rahbar M. Nutritional advice for patients with melasma in iranian traditional medicine. J Skin Stem Cell. 2016;3(1). doi: 10.17795/jssc42722.
  • 17. Gilani AH, Mehmood MH, Janbaz KH, Khan AU, Saeed SA. Ethnopharmacological studies on antispasmodic and antiplatelet activities of Ficus carica. J Ethnopharmacol. 2008;119(1):1-5. doi: 10.1016/j.jep.2008.05.040. [PubMed: 18586078].
  • 18. Tietjen KG, Hunkler D, Matern U. Differential response of cultured parsley cells to elicitors from two non-pathogenic strains of fungi. 1. Identification of induced products as coumarin derivatives. Eur J Biochem. 1983;131(2):401-7. doi: 10.1111/j.1432-1033.1983.tb07277.x. [PubMed: 6682038].
  • 19. Singh DK, Upadhyay A, Agrahari P. A review on the pharmacological aspects of terminalia chebula. Int J Pharmacol. 2014;10(6):289-98. doi: 10.3923/ijp.2014.289.298.
  • 20. Kader SMA, Bauomi AA, Abdel-Rahman M, Mohammaden TF, Rezk MM. Antioxidant potentials of (elletaria cardamomum) cardamom against Uranium hazards. Int J Basic Life Sci. 2015;3(4).
  • 21. Beier RC. A reverse phase technique for separating the linearc furano coumarins in celery. J Liq Chromatogr Relat. 2006;8(10):1923-32. doi: 10.1080/01483918508074106.
  • 22. Luszczki JJ, Wojda E, Andres-Mach M, Cisowski W, Glensk M, Glowniak K, et al. Anticonvulsant and acute neurotoxic effects of imperatorin, osthole and valproate in the maximal electroshock seizure and chimney tests in mice: a comparative study. Epilepsy Res. 2009;85(2-3):293-9. doi: 10.1016/j.eplepsyres.2009.03.027. [PubMed: 19406619].
  • 23. Ibn Sina H. Canon of Medicine. Beirut: Dar Ehya al-tarath al-arabi; 2005.
  • 24. Razi MIZ. Al-Hawi fi tebb. Beirut: Dar Ehya al-tarath al-arabi; 2001.
  • 25. Madari H, Jacobs RS. An analysis of cytotoxic botanical formulations used in the traditional medicine of ancient Persia as abortifacients. J Nat Prod. 2004;67(8):1204-10. doi: 10.1021/np049953r. [PubMed: 15332833].
  • 26. Barz W, Bless W, Borger-Papendorf G, Gunia W, Mackenbrock U, Meier D, et al. Phytoalexins as part of induced defence reactions in plants: their elicitation, function and metabolism. Ciba Found Symp. 1990;154:140-53. discussion 153-6. [PubMed: 2086034].
  • 27. Bora KS, Sharma A. The genus Artemisia: a comprehensive review. Pharm Biol. 2011;49(1):101-9. doi: 10.3109/13880209.2010.497815. [PubMed: 20681755].
  • 28. Iranshahi M, Amin G, Shafiee A. A new coumarin from ferula persica. Pharm Biol. 2008;42(6):440-2. doi: 10.1080/13880200490886102.
  • 29. Choi M, Choi S, Kang JS, Cho SB. Successful treatment of refractory melasma using invasive micro-pulsed electric signal device. Med Lasers. 2015;4(1):39-44. doi: 10.25289/ml.2015.4.1.39.

Featured Image:

Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments