Journal of Skin and Stem Cell

Published by: Kowsar

Injection of Autologous Fat Alone and in Combination With Autologous Platelet Gel for Nasolabial Fold Augmentation

Babak Ghasemi 1 , Seyed Mehdi Tabaie 2 , * , MirHadi Azizjalali 1 , Hoda Berenjiardestani 3 , Seyed Mohammad Fereshtenejad 4 , Naser Amirizadeh 5 and Mohsen Fateh 2
Authors Information
1 Department of Dermatology, Hazrat-e Rasool Hospital, Iran University of Medical Sciences, Tehran, Iran
2 Medical Laser Research Center, ACECR, Tehran, Iran
3 Skin and Stem cell Research Center, Tehran University of Medical Sciences, Tehran, Iran
4 Firoozgar Clinical Research Development Center, Tehran University of Medical Sciences, Tehran, Iran
5 Research Center of Iranian Blood Transfusion Organization, Tehran, Iran
Article information
  • Journal of Skin and Stem Cell: September 1, 2015, 2 (3); e35681
  • Published Online: September 29, 2015
  • Article Type: Research Article
  • Received: July 11, 2015
  • Accepted: September 19, 2015
  • DOI: 10.17795/jssc35681

To Cite: Ghasemi B, Tabaie S M, Azizjalali M, Berenjiardestani H, Fereshtenejad S M, et al. Injection of Autologous Fat Alone and in Combination With Autologous Platelet Gel for Nasolabial Fold Augmentation, J Skin Stem Cell. 2015 ; 2(3):e35681. doi: 10.17795/jssc35681.

Copyright © 2015, Skin and Stem Cell Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Background
2. Objectives
3. Patients and Methods
4. Results
5. Discussion
  • 1. Carruthers JDA, Carruthers A. Facial Sculpting and Tissue Augmentation. Dermatol Surg. 2005; 31: 1604-12[DOI]
  • 2. Butterwick KJ, Lack EA. Facial volume restoration with the fat autograft muscle injection technique. Dermatol Surg. 2003; 29(10): 1019-26[PubMed]
  • 3. Rodríguez-Flores J, Palomar-Gallego MA, Enguita-Valls AB, Rodríguez-Peralto JL, Torres J. Influence of Platelet-Rich Plasma on the Histologic Characteristics of the Autologous Fat Graft to the Upper Lip of Rabbits. Aesthet Plast Surg. 2010; 35(4): 480-6[DOI]
  • 4. Marx RE. Platelet-rich plasma: evidence to support its use. J Oral Surg. 2004; 62(4): 489-96[DOI]
  • 5. Pietrzak WS, Eppley BL. Platelet rich plasma: biology and new technology. J Craniofac Surg. 2005; 16(6): 1043-54[PubMed]
  • 6. Valle AD, Sammartino G, Marenzi G, Tia M, Lauro AED, Ferrari F, et al. Prevention of postoperative bleeding in anticoagulated patients undergoing oral surgery: use of platelet-rich plasma gel. J Oral Surg. 2003; 61(11): 1275-8[DOI]
  • 7. Freymiller EG, Aghaloo TL. Platelet-rich plasma: ready or not? J Oral Maxillofac Surg. 2004; 62(4): 484-8[PubMed]
  • 8. Baum C, Arpey C. Normal Cutaneous Wound Healing: Clinical Correlation with Cellular and Molecular Events. Dermatol Surg. 2006; 31(6): 674-86[DOI]
  • 9. Kaufman MR, Miller TA, Huang C, Roostaeian J, Wasson KL, Ashley RK, et al. Autologous fat transfer for facial recontouring: is there science behind the art? Plast Reconstr Surg. 2007; 119(7): 2287-96[DOI][PubMed]
  • 10. Azzena B, Mazzoleni F, Abatangelo G, Zavan B, Vindigni V. Autologous platelet-rich plasma as an adipocyte in vivo delivery system: case report. Aesthetic Plast Surg. 2008; 32(1): 155-8[DOI][PubMed]
  • 11. Torio-Padron N, Baerlecken N, Momeni A, Stark GB, Borges J. Engineering of adipose tissue by injection of human preadipocytes in fibrin. Aesthetic Plast Surg. 2007; 31(3): 285-93[DOI][PubMed]
  • 12. Hom DB, Linzie BM, Huang TC. The Healing Effects of Autologous Platelet Gel on Acute Human Skin Wounds. JAMA Facial Plast Surg. 2007; 9(3): 174-83[DOI]
  • 13. Wrotniak M, Bielecki T, Gazdzik TS. Current opinion about using the platelet-rich gel in orthopaedics and trauma surgery. Ortop Traumatol Rehabil. 2007; 9(3): 227-38[PubMed]
  • 14. Tamura E, Fukuda H, Tabata Y. Adipose tissue formation in response to basic fibroblast growth factor. Acta Oto-laryngologica. 2007; 127(12): 1327-31[DOI]
  • 15. Alam M, Gladstone H, Kramer EM, MURPHY JP, Nouri K, Neuhaus IM, et al. ASDS guidelines of care: injectable fillers. Dermatol Surg. 2008; 34-48
  • 16. Hall M, Heffelfinger R. Autologous Fat Transfer as a Facial Filler: Current and Future Applications. Curr otorhin. 2015; 3(1): 33-41
  • 17. Baumann LS, Shamban AT, Lupo MP, Monheit GD, Thomas JA, Murphy DK, et al. Comparison of smooth-gel hyaluronic acid dermal fillers with cross-linked bovine collagen: a multicenter, double-masked, randomized, within-subject study. Dermatol Surg. 2007; 33 Suppl 2-35[DOI][PubMed]
  • 18. Steed DL. Clinical evaluation of recombinant human platelet-derived growth factor for the treatment of lower extremity ulcers. Plast Reconstr Surg. 2006; 117(7 Suppl): 143S-9S[DOI][PubMed]
  • 19. Shah P, Keppler L, Rutkowski J. A review of platelet derived growth factor playing pivotal role in bone regeneration. J Oral Implantol. 2014; 40(3): 330-40[DOI][PubMed]
  • 20. Broughton G, Janis JE, Attinger CE. The basic science of wound healing. Plast Reconstr Surg. 2006; 117(7 Suppl): 12S-34S[DOI][PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

Search Relations:



Create Citiation Alert
via Google Reader

Readers' Comments