Journal of Skin and Stem Cell

Published by: Kowsar

Topical Diclofenac 3% Gel for Actinic Keratosis May Induce Terminal Hair in Male Androgenetic Alopecia: A Report of Three Cases

Helena Collgros 1 , * , Joaquin Sola Ortigosa 1 and Maribel Iglesias-Sancho 1
Authors Information
1 Department of Dermatology, Hospital Universitari Del Sagrat Cor, Barcelona, Spain
Article information
  • Journal of Skin and Stem Cell: December 31, 2015, 2 (4); e33470
  • Published Online: December 26, 2015
  • Article Type: Case Report
  • Received: September 29, 2015
  • Revised: November 21, 2015
  • Accepted: December 19, 2015
  • DOI: 10.17795/jssc33470

To Cite: Collgros H, Sola Ortigosa J, Iglesias-Sancho M. Topical Diclofenac 3% Gel for Actinic Keratosis May Induce Terminal Hair in Male Androgenetic Alopecia: A Report of Three Cases, J Skin Stem Cell. 2015 ; 2(4):e33470. doi: 10.17795/jssc33470.

Copyright © 2015, Skin and Stem Cell Journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License ( which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited.
1. Introduction
2. Case Presentation
3. Discussion
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  • 2. Sakr FM, Gado AM, Mohammed HR, Adam AN. Preparation and evaluation of a multimodal minoxidil microemulsion versus minoxidil alone in the treatment of androgenic alopecia of mixed etiology: a pilot study. Drug Des Devel Ther. 2013; 7: 413-23[DOI][PubMed]
  • 3. Mahe YF, Michelet JF, Billoni N, Jarrousse F, Buan B, Commo S, et al. Androgenetic alopecia and microinflammation. Int J Dermatol. 2000; 39(8): 576-84[PubMed]
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  • 5. Muller-Decker K, Leder C, Neumann M, Neufang G, Bayerl C, Schweizer J, et al. Expression of cyclooxygenase isozymes during morphogenesis and cycling of pelage hair follicles in mouse skin: precocious onset of the first catagen phase and alopecia upon cyclooxygenase-2 overexpression. J Invest Dermatol. 2003; 121(4): 661-8[DOI][PubMed]
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  • 7. Garza LA, Liu Y, Yang Z, Alagesan B, Lawson JA, Norberg SM, et al. Prostaglandin D2 inhibits hair growth and is elevated in bald scalp of men with androgenetic alopecia. Sci Transl Med. 2012; 4(126): 126ra34[DOI][PubMed]
  • 8. Michelet JF, Commo S, Billoni N, Mahe YF, Bernard BA. Activation of cytoprotective prostaglandin synthase-1 by minoxidil as a possible explanation for its hair growth-stimulating effect. J Invest Dermatol. 1997; 108(2): 205-9[PubMed]
  • 9. Nelson C, Rigel D, Smith S, Swanson N, Wolf J. Phase IV, open-label assessment of the treatment of actinic keratosis with 3.0% diclofenac sodium topical gel (Solaraze). J Drugs Dermatol. 2004; 3(4): 401-7[PubMed]
  • 10. Sharquie KE, Al-Nuaimy AA, Kadhum WJ. Treatment of alopecia areata by topical diclofenac sodium gel in comparison to benzoyl peroxide gel. A novel single blind therapeutic clinical trial. Saudi Med J. 2006; 27(7): 1079-81[PubMed]
Creative Commons License Except where otherwise noted, this work is licensed under Creative Commons Attribution Non Commercial 4.0 International License .

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