Journal of Skin and Stem Cell Journal of Skin and Stem Cell J Skin Stem Cell http://www.journalssc.com 2423-7086 10.5812/jssc. en jalali 2017 6 26 gregorian 2017 6 26 2 1
en 10.17795/jssc25770 An Unusually Ulcerative Eccrine Poraoma: A Case Report and Review An Unusually Ulcerative Eccrine Poraoma: A Case Report and Review case-report case-report Introduction

Eccrine poroma is a benign neoplasm thought to derived from Eccrine sweat glands. Recently, studies have shown wide distribution of Eccrine poroma, including acral, face, and abdomen forms.

Case Presentation

We reported a 65-years-old woman with rapidly growing 5-cm ulcerative Eccrine poroma with active bleeding since one year prior to presentation.

Conclusions

Although rapid growth and bleeding can be related to malignancy and biopsy is necessary to be performed, benign lesions can present with mentioned symptoms. Physicians should be aware that benign poroma can present as an ulcerative and large neoplasm.

Introduction

Eccrine poroma is a benign neoplasm thought to derived from Eccrine sweat glands. Recently, studies have shown wide distribution of Eccrine poroma, including acral, face, and abdomen forms.

Case Presentation

We reported a 65-years-old woman with rapidly growing 5-cm ulcerative Eccrine poroma with active bleeding since one year prior to presentation.

Conclusions

Although rapid growth and bleeding can be related to malignancy and biopsy is necessary to be performed, benign lesions can present with mentioned symptoms. Physicians should be aware that benign poroma can present as an ulcerative and large neoplasm.

Eccrine Poroma;Ulcerative;Presentation Eccrine Poroma;Ulcerative;Presentation http://www.journalssc.com/index.php?page=article&article_id=25770 Elham Behrangi Elham Behrangi Department of Dermatology, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran Department of Dermatology, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran Nasrin Shayanfar Nasrin Shayanfar Department OF Pathology, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran Department OF Pathology, Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran Tanaz Hoseinzade Fakhim Tanaz Hoseinzade Fakhim Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran Shooka Esmaeeli Shooka Esmaeeli Students Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, IR Iran Students Scientific Research Center (SSRC), Tehran University of Medical Sciences, Tehran, IR Iran Faezeh Jannati Faezeh Jannati Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran Zahra Azizian Zahra Azizian Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran; Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran. Tel: +98-9122788611 Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran; Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, IR Iran. Tel: +98-9122788611
en 10.17795/jssc30058 Safety of Anti-TNF-α Therapy in Patients With Psoriasis and Concomitant Hepatitis C Virus Infection Safety of Anti-TNF-α Therapy in Patients With Psoriasis and Concomitant Hepatitis C Virus Infection letter letter Psoriasis;Hepatitis C Virus;Tumor Necrosis Factor-alpha;Cytokines;Inflammation Psoriasis;Hepatitis C Virus;Tumor Necrosis Factor-alpha;Cytokines;Inflammation http://www.journalssc.com/index.php?page=article&article_id=30058 Zohreh Jadali Zohreh Jadali Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IR Iran; School of Public Health, Tehran University of Medical Sciences, Tehran, IR Iran; Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IR Iran. Tel: +98-2122215558, Fax: +98-2122674977 Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IR Iran; School of Public Health, Tehran University of Medical Sciences, Tehran, IR Iran; Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, IR Iran. Tel: +98-2122215558, Fax: +98-2122674977
en 10.17795/jssc3028 Skin Aging Remedies in Traditional Persian Medicine Skin Aging Remedies in Traditional Persian Medicine review-article review-article Conclusions

Reported herbal drugs might be beneficial for further studies for the management of skin aging and aging process.

Results

Skin aging begins with whole body aging process and entire body gets cold and dry in elderly. Wrinkle formation is highly associated with loss of “skin natural moisture”. In the management, specific food supplements, simple massage therapy as well as herbal drugs were suggested. The current investigation was performed to show the knowledge of ancient Iranian scientists on aging process and related interventions.

Context

Traditional persian medicine (TPM) is an ancient temperamental medicine with a rich literature about aging mechanism. Temperament has an important function in maintaining the ideal healthy status of human body. Aging process and skin aging could be postponed by applying herbal medicine and some specific traditional rules.

Evidence Acquisition

The aim of this review study was gathering and discussing the mechanism of whole body aging and skin aging from perspective of TPM and introducing remedies to prevent it. Skin aging is caused by external and internal factors. According to TPM, loss of fat and water content in different skin layers is the main cause of skin aging and it could be avoided by considering simple essential commands.

Conclusions

Reported herbal drugs might be beneficial for further studies for the management of skin aging and aging process.

Results

Skin aging begins with whole body aging process and entire body gets cold and dry in elderly. Wrinkle formation is highly associated with loss of “skin natural moisture”. In the management, specific food supplements, simple massage therapy as well as herbal drugs were suggested. The current investigation was performed to show the knowledge of ancient Iranian scientists on aging process and related interventions.

Context

Traditional persian medicine (TPM) is an ancient temperamental medicine with a rich literature about aging mechanism. Temperament has an important function in maintaining the ideal healthy status of human body. Aging process and skin aging could be postponed by applying herbal medicine and some specific traditional rules.

Evidence Acquisition

The aim of this review study was gathering and discussing the mechanism of whole body aging and skin aging from perspective of TPM and introducing remedies to prevent it. Skin aging is caused by external and internal factors. According to TPM, loss of fat and water content in different skin layers is the main cause of skin aging and it could be avoided by considering simple essential commands.

Skin Aging;Medicine, Traditional;Prevention Skin Aging;Medicine, Traditional;Prevention http://www.journalssc.com/index.php?page=article&article_id=30283 Laila Shirbeigi Laila Shirbeigi Faculty of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran Faculty of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran Maryam Iranzadasl Maryam Iranzadasl Faculty of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran Faculty of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran Parvin Mansouri Parvin Mansouri Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran; Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran. Tel: +98-2122825524 Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran; Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran. Tel: +98-2122825524 Somayeh Hejazi Somayeh Hejazi Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran Skin and Stem Cell Research Center, Tehran University of Medical Sciences, Tehran, Iran Jale Aliasl Jale Aliasl Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran Traditional Medicine Clinical Trial Research Center, Shahed University, Tehran, Iran
en 10.17795/jssc29547 Unusual Presentation of Angiolymphoid Hyperplasia With Eosinophilia in a Thirty-Six–Year-Old Man Unusual Presentation of Angiolymphoid Hyperplasia With Eosinophilia in a Thirty-Six–Year-Old Man case-report case-report Case Presentation

We reported a 36-year-old man with ALHE lesion on penis and discussed the clinical and histopathological features.

Conclusions

When we have any dermal or subcutaneous lesion on genitalia, we can consider ALHE in differential diagnosis.

Introduction

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a benign slow-growing vascular proliferation characterized by dome-shaped violaceous papules or nodules. Although it is usually found in the head and neck, it is reported in liver, orbit, spleen, palate, bone, heart, blood vessels, parotid gland, and colon.

Case Presentation

We reported a 36-year-old man with ALHE lesion on penis and discussed the clinical and histopathological features.

Conclusions

When we have any dermal or subcutaneous lesion on genitalia, we can consider ALHE in differential diagnosis.

Introduction

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a benign slow-growing vascular proliferation characterized by dome-shaped violaceous papules or nodules. Although it is usually found in the head and neck, it is reported in liver, orbit, spleen, palate, bone, heart, blood vessels, parotid gland, and colon.

Angiolymphoid Hyperplasia with Eosinophilia (ALHE);Penis;Genitalia Vascular Lesion Angiolymphoid Hyperplasia with Eosinophilia (ALHE);Penis;Genitalia Vascular Lesion http://www.journalssc.com/index.php?page=article&article_id=29547 Kambiz Kamyab Kambiz Kamyab Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, IR Iran Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, IR Iran Farhad Malekzad Farhad Malekzad Skin Research Center, Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Skin Research Center, Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Safoura Shakoei Safoura Shakoei Department of Dermatology, Ziaian Hospital,International Campus,Tehran University of Medical Sciences, Tehran, IR Iran Department of Dermatology, Ziaian Hospital,International Campus,Tehran University of Medical Sciences, Tehran, IR Iran Maryam Ranjbar Maryam Ranjbar Skin Research Center, Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran; Skin Research Center, Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran. Tel: +98-2122744392, Fax: +98-2122744393 Skin Research Center, Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran; Skin Research Center, Shohada-e Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran. Tel: +98-2122744392, Fax: +98-2122744393
en 10.17795/jssc2928 Comparison of Therapeutic Response of Keloids to Cryotherapy Plus Intralesional Triamcinolone Acetonide or Verapamil Hydrochloride Comparison of Therapeutic Response of Keloids to Cryotherapy Plus Intralesional Triamcinolone Acetonide or Verapamil Hydrochloride research-article research-article Results

There was a real faster response in the first group; while groups 3 and 4 had the slowest responses to treatment. Rates of responsiveness seemed to have no significant difference between the groups, but side effects were significantly much frequent in the first group.

Conclusions

Intralesional triamcinolone acetonide with cryotherapy showed the most efficacies with more adverse effects, but intralesional verapamil with cryotherapy showed good efficacy with less adverse effects. Hence, it is a suitable alternative in the treatment of keloids.

Patients and Methods

Eighty patients (42 females and 38 males, aged 11 - 40 years) were allocated to receive one of the four treatment methods. Group 1: Intralesional triamcinolone with cryotherapy. Group 2: Intralesional verapamil with cryotherapy. Group 3: Intralesional verapamil. Group 4: Cryotherapy. Improvement of healing was measured using modified Vancouver scar scale and centimeter scale.

Objectives

The aim of this study was to compare the efficacy and safety of “intralesional triamcinolone with cryotherapy” and “Intralesional verapamil with cryotherapy”.

Background

A keloid is dysregulated fibroproliferative scar tissue in response to skin injuries, which extends beyond the wound margin. Since it has a poor response to treatment, variable therapies are used. Current therapies of keloid include intralesional corticosteroid injection, cryotherapy and various laser therapies, silicone gel sheets (pressure therapy), interferon-α-2b, 5-fluoruracil or bleomycine administration, excision followed by low dose radiation or topical imiquimod.

Results

There was a real faster response in the first group; while groups 3 and 4 had the slowest responses to treatment. Rates of responsiveness seemed to have no significant difference between the groups, but side effects were significantly much frequent in the first group.

Conclusions

Intralesional triamcinolone acetonide with cryotherapy showed the most efficacies with more adverse effects, but intralesional verapamil with cryotherapy showed good efficacy with less adverse effects. Hence, it is a suitable alternative in the treatment of keloids.

Patients and Methods

Eighty patients (42 females and 38 males, aged 11 - 40 years) were allocated to receive one of the four treatment methods. Group 1: Intralesional triamcinolone with cryotherapy. Group 2: Intralesional verapamil with cryotherapy. Group 3: Intralesional verapamil. Group 4: Cryotherapy. Improvement of healing was measured using modified Vancouver scar scale and centimeter scale.

Objectives

The aim of this study was to compare the efficacy and safety of “intralesional triamcinolone with cryotherapy” and “Intralesional verapamil with cryotherapy”.

Background

A keloid is dysregulated fibroproliferative scar tissue in response to skin injuries, which extends beyond the wound margin. Since it has a poor response to treatment, variable therapies are used. Current therapies of keloid include intralesional corticosteroid injection, cryotherapy and various laser therapies, silicone gel sheets (pressure therapy), interferon-α-2b, 5-fluoruracil or bleomycine administration, excision followed by low dose radiation or topical imiquimod.

Keloid;Cryotherapy;Triamcinolone Acetonide;Verapamil Keloid;Cryotherapy;Triamcinolone Acetonide;Verapamil http://www.journalssc.com/index.php?page=article&article_id=29284 Parvin Jannati Parvin Jannati Department of Dermatology, Skin Research Center, Shohada-e- Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Dermatology, Skin Research Center, Shohada-e- Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Saeed Aref Saeed Aref Department of Dermatology, Skin Research Center, Shohada-e- Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Tel: +98-2122741507, Fax: +982122744393 Department of Dermatology, Skin Research Center, Shohada-e- Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran; Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Tel: +98-2122741507, Fax: +982122744393 Ahmad Amin Jannati Ahmad Amin Jannati Department of Dermatology, Skin Research Center, Shohada-e- Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Dermatology, Skin Research Center, Shohada-e- Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Faezeh Jannati Faezeh Jannati Department of Dermatology, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran Department of Dermatology, Rasool Akram Hospital, Iran University of Medical Sciences, Tehran, Iran Hamideh Moravvej Hamideh Moravvej Department of Dermatology, Skin Research Center, Shohada-e- Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Dermatology, Skin Research Center, Shohada-e- Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran